avoid mixing woofers.
212 cabs seem to be a sweet-spot for size, weight, and power (unless you are in a mega doom metal rasta dubstep band). some will argue two 112s for a portable, modular rig. super-12 drivers have been a game changer, but they aren't cheap. lots of love for the TecAmp m212, the Berg CN 212, and the Baer ML 112 and 212 cabs. the Barfaced cabs are awesome (i've heard), but spendy. Thunderchild and Fearful/less designs also have some big fan-bois here (and for good reason). check some mega-threads.
when all of your wishes are granted, many of your dreams will be destroyed