Never done an A/B test on 2 210's vs a 410 although I have owned one of each. I recently sold both and switched to a pair of DNA 112's.
My 410 was an awesome cab but way too much power for the gigs I play, and my 210 was overkill as a practice cab. Before I sold my 410 I A/B'd it against my 112's, and found the pair of 112's to be more than enough volume and better overall tone.
You might want to consider the 2 112's as another option unless you need a massive amount of output.
"Lemme tell you something Pendejo.."
The 410 is just way too loud for the majority of bar gigs I used to do. I can get away with just one DNS 210 for many gigs - granted my tone had plenty of low mids, grind and midrange in it. Still had some decent low end response though. I have run one or two DNS 210's for about 100 gigs and I have never needed anything more than that. All going up against two guitar players who understand volume constraints coupled with a VERY LOUD punk style drummer. One 210 for smaller gigs, two 210's vertically stacked for bigger gigs.
The single 12 DNS cab has a great tone with more high end roll off in the 2khz range than the 210. For pick playing, the extra grind and clarity from the 210 cabinet is crucial for me. The 112 cab however, had a warm fingerstyle tone immediately. Any vintage tone enthusiasts or those who like thumpy/flatwound tones should go grab some of these cabs. Not to say the 112 was lacking in high end, it just has less of it to start.