Some 6 years ago i got the chance to compare the EBS proline 2000 4x10 and the EBS neo 4x10 in a shop. Used an EBS HD350 amp.
They sounded much the same but the neo 4x10 lacked some bottom compared to the non-neo. I ended up buying the proline, been using it ever since. These cabs are built like tanks and can take a beating from your amp as well. I never had issues, not even when it got mistreated by defective amps (power unit failures, tubes breaking down, power-amp problems).
With a 350 amp, i hear the Neo 110+112 is a killer setup.
I still wonder how my current Fafner would sound through a neo410 combined with a neo212 though

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Good luck!