The 4X10. Handles the most power, brings the most volume and is ridiculously versatile. But then again I have been one of Larry's converts since the days of the first aluminum cones.
I own a 1X15, a 4X10 and a 1x12 HyDrive. The 112 gets most of the small and medium gigs. The 410 gets medium and large gigs. The 115 usually only comes out to play with my 410 at outdoor festivals and large outdoor events. Until I got the 112 my regular every day rig was a LH 500 and the 410.
Endorsing Artist - Petillo Masterpiece Guitars, J. Backlund Design, Vivid Amps, Hartke, Bitchstraps