it's always interesting to protect our gear with road case.
Some of them like Mikeddd showed is made in two pieces. One bottom where the cab stands and one top (like a hat) that is removed for use.
For smaller cab like 2x10, 1x15 and 4x10, you can use the top of the road case as a stand for your cab.
Other type of cases consist of a front lid that is removed for playing
None of them will change your tone.