Which cab do you like the sound of the most?
Get another one of those.
You may be trying to eq for the different cabs and you'll never get it right.
Spend some time with the SWR.
Crank the pre til light flashes then back off just a hair, no more AE than 11:00, tone flat, reduce treble a little, no effects, crank Master for what volume you need.
Use speakon cable too.
Also a 750x can make a powerful roar with one 4x10 Goliath. If you turn it up.

(I've never tried a Fender) The idea though is sometimes less is more.