When you say "tuned up" I'm assuming you mean you're tuning "down" to those pitches, right?

But just using that phrase as slang...
Listen to K-H. I just ordered a custom set of his strings from him b/c I tune my 5'er (or will once it gets here) G or ACGCF, which is one half step down from even what you're doing, and I have some HUGE honkin' strings on the B and E strings, but to do it correctly, it looks to be the correct way.
I'll have some good reports coming soon, as I'm a 5-year long DR user, so it'll be a good comparison as lots of guys here use Hi Beams and Lo Riders like I do/have.