Flatwounds kick ultimate reggae @$$!!!!!! Been looking recently into getting a reggae/dub tone. After multiple threads/gear settings, switching to flats made the biggest difference.
Oh, and as far as gear settings, cut the hell out of the treble/high mids (around 750Hz IME), and boost the bass a little (~8-10 dB, again IME). Oh and if you have a passive bass, close the tone knob.
