i tried my first set-up today, specifically lowering the action and fixing the intonation of my Epi Blackbird. reading around the TB forums, i felt pretty ready, and knowing that this should not be too hard.
this presented a couple of revelations for me.
First: the screws are made of a very soft metal, that will bend to the might of a normal screwdriver. The nice black finish on the top of them was pretty much ruined.
Secondly: The screws become much easier to turn if you slack the strings a bit before you try to turn them. (why did i not think of this before?!?

)
Thirdly: I knew that it would be best to tighten the screws bit by bit, and take them in turns. When a screw won't go any further, that does not mean that you can still try to tighten the other screws more, actually this means you should show great care, or you might end up with one screw, and the screw-socket poping out. just like this: (sorry for the poor quality. you should be able to see that the socket is out of place anyways.)
So, i hope you learned from my mistakes. Don't become an expert because you read up on a subject on the tubes, and preferably get someone with the know-how, to show you how it's done the first (couple of) time(s).