I live in the area... There are many clubs and music venues. Some of the best places are the Jazz Factory (downs stairs is a really fancy restaurant with big band jazz. Upstairs is a Martini/cigar bar with jazz, blues, and different types of acoustic music on the weekends. Humphries is a good place... music 7 nights a week. Sammy T's if you like 80's music...lol
Check out
http://www.thetoe.cc It is a site of local bands, music, food, events, etc...