A podcast I listen to, Keith and the Girl are doing a world record 72 hour straight live podcast with proceeds made (ie donations) going to fund asperges syndrome research.
Its currently at about hour 36 and is quite funny. Its out of NYC so its early in the morning now, but if you want to check out the goings on go to:
www.katg.com/livevideo
I can't guarantee the language will always be clean or that the topics won't be offensive from time to time, but if you want to check out a cool show and some funny people doing something for charity check it out. The show is having various guests and friends coming in and out of the mics to keep it going.
For a minor bit of trivia, the Girl, Chemda, was a vocalist for Delirium and Conjure One who are projects of Rhys Fulber, ex Front-Line Assembly.
Anyway, I highly recommend.