Originally Posted by RickenBoogie
"Best" is what sounds best to you. There are no rules other than use your ears.
Search for things like "effects order," signal chain order," "pedal order," etc and you'll find quite a few threads and opinions on the matter. But in the end, it's all bout what works/sounds best for you and your application.
Example: Spencer (designer of 3Leaf Audio pedals) runs his PWNZOR as close to the front of his chain as he can, while I'm exactly opposite and run it as close to last as possible.