| Yeah even with the list of pedals, we don't have enough information. What exactly is the "2loop" pedal? Is it a mechanical true bypass loop switcher? If so, what is in each loop--and are any pedals NOT in the loops? Bass active or passive? Are any pedals "on always", not bypassed?
Plus, there are good buffers and bad buffers. A bad buffer will give you tone loss problems--so you could put the world's most awesome buffers at both beginning and end of your chain, and if a crappy buffer is causing tone loss in the middle, the tone will still suck. So you'll want to carefully examine whether a bunch of your pedals in series are just murdering your tone; if they are, an added buffer will not help.
Where a buffer can help is if you have a passive instrument, a long cable or two, or a long true-bypass fx chain.
Generally you'd put the buffer between a passive bass and the pedalboard. The exception would be if you happen to find out that the output impedance of your last pedal is very high, and the input impedance of your amp is very low, and you've got a long cable between them. Pretty esoteric and uncommon, but it can happen. | 
