Usually playing a Jazz bass, sometimes a P with these settings:
Bass: 11:30 - Noon
Mid Freq: 1:30
Mid Level: 3:00
It may look like a really grindy/honky middy tone but I play through a HUGE house system on weekends at church and this setting just rocks in a big rock band mix. Super clear I'm usually up against at least 2 electrics (sometimes up to 4), keys, acoustic, drums, 3-6 vocalists, and occasionally tracks run through ProTools, so I don't have a lot of sonic space, and clarity is definitely at a premium.
Here's a sample for you: http://vimeo.com/51780605
Music starts at 3:10
If you just have a quick second to reference, jump to 5:30 and listen.
The setup in the video is my Jazz bass drop-D tuning (70's pup spacing), Dunlop SS strings, Bullet cable into my board (see my sig line) into FOH.