Ah, so I was too lazy earlier to notice the video had the title listed, so I looked up a few live versions. Personal opinion, sounds like a Sansamp to me. From the passing frames in some vids my bet is on a Tech21 sansamp programmable bddi. That said, I have an ODB-3, and you could actually get close to that sound with it. Try the Balance dialed back at around 8 o'clock or so (b/c it sounds like he has a lot of his clean signal mixed in) and keep the Gain knob dialed back in the same range, add til you get enough overdrive.
Eat all your veggies. And don't bang the dillies.