In my experience, the reason most people lose interest in the multi fx is that they dont put in the time to work with them. Cant be blamed, who has that much time, its better spend playing. For a multi i would vote for Zoom B2.1u which u can get close to the 100 range in price.
The best multi for dummies is probably pedals...but for that price you cant get much, although some of these have multi fx going on and are very easy to use. check them out. hand made, high quality sounds that u wont grow out of
http://www.zcatpedals.com/?dir=hot