A lot of buzz between songs could point to a shielding/grounding issue. As for pickups, fenders are highly regarded by many, if there are not any tonal issues you are trying to change, I wouldn't bother. Replacing pickups doesn't necessarily make it sound better, just different. If you want something with more high end or low end, or flatter or more scooped, etc, then you can shop around and see what you find, and new pickups might make sense.
Colorado Club #667