A Tele, but I'm a Tele freak.
A MIM Tele or Strat will probably be ok, but much like picking out a MIM Jazz or Precision bass, play a few to find one that sounds and feels good.
NI Guitar Rig is indeed pretty good. I tried out the demo and I was honestly surprised at its sound quality. I would have probably gone ahead and bought the full version if I didn't already have a bunch of gear that already suited my needs.