| If you're talking about the overall design of the instrument and its geometry: That's equivalent to taking a standard neck, and when mounting it to the body, instead of putting the neck centerline on the body centerline, put one neck edge parallel to the body centerline. (And adjusting the bridge position as appropriate.) Which, in effect, is the same as rotating the body, if you think of it as mounting the body to the neck instead of mounting the neck to the body.
If you're talking just about the neck construction: it's probably not advisable, since by tapering one side only you now end up with an unbalanced (stress-wise, not weight-wise) design, with the average line of grain running on a diagonal with respect to the string tension and the effective neck axis, instead of dead parallel in line with the string tension and major axis. | 
