Bernard Edwards cut most of the classic Chic tunes on his 2 band Stingray strung w/ flats - the tone has more of a smooth, midrange 'burp' as compared to what most people associate with the typical Ray sound. So I definitely think it's possible.
"What I do, nobody notices until it stops." - Garry Tallent
Spector Club #13, Blue Bass Club #13, NJ Bassists Club #98, Bassists w/ Beards Club #66