I use my Radial Mix/ Blender to inject one or more of my OD/ Fuzz/ Distortion effects into my signal chain. I have it second in my chain (my tuner is first) and, live, I often have 2 instruments running into it for quick changes without having to retune, etc.
I use this for both guitar and bass. With bass, I have the blend set between 50%-60% wet, depending on the specific bass that I'm using. With guitar, I set the blend to 100% wet, because I'm not concerned about preserving my original guitar tone (but if I want to, I can, thanks the the Mix Blender ).
Previous to Radial releasing the Mix Blender, I'd used the Boss LS-1 but much preferred the simplicity and relative quietness of the Radial once I got to try one out. It has lived on my pedalboard ever since.