2 identical 1 x 12's is the way to go. Modular and efficient if you're packing light and only need one 8 ohm load.
Although I agree with the above 4 posts (my 1x12 weighs only 23 lbs, and the 3012 is plenty potent!), having both 1x12 and 2x12 cabs to choose from, I prefer a single 2x12 cab for a quicker setup. The single 12 cab is definitely easier to move, and the pair of 1x12s is easier to fit into the car than the 2x12 cabs...
Thanks gang. I asked because I'm thinking of going back to 12" speakers. Right now I'm playing thru a GK MB115 and while I do like it and it serves my needs I find I miss that 12" sound that I use to play thru many years ago. Sometime this year I'm thinking I'd like to try out a GK MB 500 thru either a Neo 2x12 cab or thru 2, 1x12 Neo cabinets. Offhand the 2, 1x12 cab's sounds more appealing because of my back. I'm at the point where I'm better off making a few extra lighter trips as opposed to making just a few heavier trips going back and forth. Would the 2, 1x12's handle a low B with no problem? When I played thru 12's I was only using a 4 string bass. Thanks for your time.
There is a ton of options with single 12 cabs. You would likely be best to go for something lightweight and portable. I have a pair of Mesa PH112 cabs and they are fantastic tonewise but not the most ergonomically well designed cabs for transport. Something you can pick up with one hand is the way to go. The GK Neo's would be one of my first choices!
I have both. 1-Aguilar DB212 and 2-Aguilar DB112's. There very little difference in the sound the DB212 is very slightly fuller but it almost negligible. You are not losing anything going with either setup. The 112's are better for small stages, but only by a little.
I've had both setups. IMHO, a single 2x12 enclosure is much easier to handle than two 1x12 boxes. Why? Simply put, the single 2x12 takes up less space, if it has casters you can move it with one hand (try that with two boxes), and thanks to today's neo technology you can have a 2x12 enclosure that weighs almost nothing and will (almost always) weigh less than two separate boxes. People say you get flexibility with two boxes, but, as someone who has had to schlep gear upwards of 30 different times in one week to make rehearsals, studio sessions, and gigs, I've found it so much easier just to use the single 2x12 cabinet for everything. You always have your full rig so you're never under-prepared, and it takes less time to setup because you only need to move and put together one cab. I can move my Genz Benz Neox212t, my cable bag, my amp head, and my bass all in one trip from my car. I have never been able to do that with two cabs.
Another 1x12 person here. I was just able to compare quite a few 12" cabs at a local shop yesterday: Aguilar DB212 Aguilar DB112 (x2) Aguilar SL112 (x2) Bergantino CN212 Bergantino CN112 (x2) GK MBE Series II 2x12 Hartke HyDrive 112 (x2) The Aggie SL's had been my "dream rig" for quite a while, but I brought traded in my Avatars (B210 and B212, both neo) and brought home a pair of Berg 1x12's. Wow! Like others have mentioned... Modular, light, killer sound, pack well, etc. 5sg.
If you're actually going to leave separate 112s in different locations (I do not like leaving gear anywhere, especially nice gear), then 112 x 2. Otherwise a single 212. 1 trip. Not hard to schlepp one of these, neither too large nor too heavy. You always have more displacement/volume on hand. And the amp's volume control does move to the left if you only want/need lower output.
For me, a 4x12 would be total overkill. I just don't need anything that size and the weight alone would probably do my back in once and for all! Right now I'm just playing covers....Beatles to Black Keys, Eagles to Elvis Costello. We're not overly loud onstage either. Got a drummer who's solid but not over bearing, an acoustic guitar player and our other guitar player goes thru a Vox AC15. I'm in no hurry to rush out and buy either. I like doing my homework and part of that is asking questions to those who have what I may be interested in to see how it's working for them. But I have read a lot of good things about GK's Neo 2x12 cab's.
Another 212 vote here. I find a light and upright 212 easier to move than 2 x 112s. For my needs, a 2 x 112 rig isn't more versatile, since I'd almost always rather have a nice 212 on a gig than a single 112 (handles louder gigs, and gets the sound closer to my ears on quieter gigs). I'd feel differently if my gigs involved getting through subway turnstiles. Luckily, that's not an issue here.