2 mesa 1000's????

sure - those cabs are four ohms each so you'll need to run one cab out of each side in stereo mode rather than bridged mono. it will put 360 watts into each cab which should drive them just fine being that the GK's are conservatively rated.
 
sure - those cabs are four ohms each so you'll need to run one cab out of each side in stereo mode rather than bridged mono. it will put 360 watts into each cab which should drive them just fine being that the GK's are conservatively rated.

360?? not to be arguementative, but i think it pumps 540 each side.
 
it will do 1080W bridged mono into a 4ohm minimum load which would be one 4 ohm cab or two 8 ohm cabs. the PH are 4 ohms each, so you can't run it in bridged mono mode - that would be 2 ohms. you can run one cab out of each channel - each channel will put out 360W into 4 ohms. you could also run both cabs out of one side of the amp so that it would put out 540 into 2 ohms, but each cab would only be getting 270 watts.

JR