I've been doing some research to see if there were any differences between a 2x12 cabinet and 2 1x12 cabinets (besides the portability advantage). Apparently there are some sonic differences (how subtle that difference is debatable). I emailed Bergantino and Epifani and here's what they had to say: Jim Bergantino - "Yes! They are two completely different speakers. In fact they don't even share the same woofer. The 112 is designed to be more punchy and focused with a very defined and detailed midrange. It also has a somewhat limited low end response. You can hear every note on the B string distinctly, but you won't "feel" it like you would on the 212, which has a warmer more extended sound. The 112 is a great cabinet, and two will sound amazing. It would definitly work for rock, but you may feel a bit limited in the low end if you play a lot of blues since it doesn't have the warmth of the 212. If you have the opportunity to check it out you may be pleasantly surprised! I hope this helps." Epifani - "We have two 212 cabinets: the T-212 and the T-212D. The T-212 is the one on our website and the T-212D is a 212 configuration inside a box the size of our T-410. The larger size extends the low end. The T-212D is much deeper sounding than the T-212 and two T-112's. Two T-112's have a similar sound to the T-212 though. Two T-112's give you alittle more high end because there are two tweeters. Otherwise the T-212 and two T-112's are almost the same." What does everyone think? Is this pretty much right on or do you have different opinions? Thanks!