Hi Guys (and gals)! I have finally moved and I am in the process of adapting my setup to my new practice/work/office space! Until now, I have used a mixer with a built in USB interface, but in my new setup it will be slightly different. My setup is as follows: All sources (bass, guitar, keyboard, mics etc) run into a Yamaha mixer (through DI's when neccessary). From the mixer I have various outputs going to different amps, monitors etc, and a L + R going to another mixer that controls the inputs/outputs to the rest of the house etc. I would like to add an interface into the equation, but I have realised that I am really out of touch! I was thinking that I would like to hace a permanent L+R running to the interface connected via USB to the PC (running Win7) but also have an extra input for plugging in bass etc directly, without having to change connectors. I was looking at the M-Audio Mobilpre MKII, which has a switch to choose between the rear inputs and the front inputs, but I have read on various occasions that M-Audio "aint what it used to be!" I also liked the Yamaha Audiogram, but read also that the direct monitoring is hard wired, so you always get a clean signal (not that I usually use effects, but who knows!) I am now looking at the Focusrite Scarlett 212, which only has 2 inputs. So now, my questions to (you) the experts! Is there anything negative about running the instruments through the mixer before the interface, or would direct be better? If I were to use aux sends to the interface, instead of the outputs, I could choose which channel I wanted to assign to each input. Is this a good or bad idea? What are your opinions on the Scarlett? Better alternatives? Thanks to all for any input you may have!!