I've owned both and will chime in with more input when I have some time. But ask KJung. He'll give you good opinions of both and will most likely steer you in the way of the M-Pulse600. I love the DB750. There are very few heads that can compare to such a head of sheer power and solid engineering. My Titan V12 is one of those heads though... You'll have more flexibility with the 600 (the semi-para eq), but you'll have more headroom and girth in your sound with the DB750. The 750 has a very distinct tone, which can vary depending on the bass, cab, efffects etc that you pair it with, however it does have a signature tone. If you love it, you love it, if you don't...then you don't. But I loved it. I wish I had another one of these. In a perfect world where i had another 2k to spend on a head and I worked out often enough to schlep around 45lbs constantly.