I've noticed that when i play notes on the E and A string i keep my right hand and wrist (i'm lefty btw) relatively straight, but when i play notes on the higher strings my wrist tends to turn to where the pinky side of my hand is facing more towards the ground. this might be a terrible description but i did my best should i try to fix this, or is it natural and I should just play how I feel comfortable?
I'm not sure exactly what you mean, but generally it is best to have the wrist(s) straight. You are a lefty so you are talking about the fretting hand. This clip may help : Developing Safe Left Hand Technique for Bass Guitar - YouTube