I'm filling in for a bassist who's wife smashed his axe , and one of the tunes calls for high E past the 20 frets on my old school Fenders. Of course, the gearhead solution is to seize on the excuse for new gear and get a good 22+ fret bass (Lakland, anyone?), but I'm thinking about tuning up a full step to see what happens. I'm sure I'll need to watch neck relief closely, and make trussrod adjustments if necessary. Also I assume light gauge strings would be better to reduce the tension. Any other adjustments I should make or issues I should watch for?