My take: A tube is a high impedance, high voltage but low current device. In order for them to produce a higher wattage than 100 or so watts you need to increase the voltages that they operate on. 100w around 450 to 500V, 200W 550 to 600V, 300W around 600 to 700V 1000W in excess of 1KV. Only transmitter tubes are logical in this range and they need cooling systems to work. Efficiency in the ball park of 15 to 20% means an independent specialized AC feed. All of this adds weight, cost and complexity. Not a reasonable choice for a travelling musician.
Compare to a Class D amplifier delivering a couple of kilowatts of power weighing 15 pounds with efficiencies closing on 100%
Paul