As others have said, this is often caused by a problem with your instrument cable. Try another cable. Sometimes it goes away if you change the direction that your amp is facing. Also, make sure that your cable is lying flat on the floor with no loops in it. Make sure that the nut on your input jack is tight. It could also be caused by a bad ground connection inside the amp at the jack.
If all else fails, you might be able to fix it by isolating the input jack from the chassis (there are washers available to do this), then installing a small capacitor (10 nanofarads) from the jack ground to chassis. I would speak to the manufacturer before you started getting into measures like this.
...and if you have any large transmitters nearby, your out of luck.