Well, where I live I have to drive 6 miles just for a quart of milk or anything, and that's still in either West Podunk or East Podunk, depending on the store...
It's about 50 miles (1:10 or so) to the other side of Buffalo to rehearse, but we don't even rehearse every month unless working on new stuff. With 8 records to draw from, we all know the tunes and don't need to work on back catalog stuff unless there's something high profile & we want to polish things up.
I drive 40 miles each way into Buffalo to jam with friends every Saturday I'm available. That's just a casual hang - no organization or gigs involved. That takes just under an hour, maybe 90 minutes if it's snowing hard and I take back roads to avoid the morons on the mains.
I have put a lot of consideration into this matter over the years. We made a decision a decade ago to move to a pretty remote area, then a few years after that I decided (and SWMBO kindly agreed) to get active in music again. The population out here is pretty thin - most surrounding school districts graduate less than 80 kids per class. There's few venues and very few musicians worth my time and effort. I figure what's so bad about spending a couple extra hours in the car every month to go play music I love with people I love? It beats sitting at home wishing I had something cool to do or playing with guys that need 20 rehearsals to get ready for every gig.
We'll probably move into a more "metro" location when the kids are done with school (15 years, but who's counting?).