I've got a macbook pro and a audiophile firewire and an axiom 25. The audiophile seems to be working much better with this most recent revision of the m-audio drivers. For a while there, on the last revision, I was getting some weird stuttering from the front panel knobs when using them while playing audio. I use Logic Pro and Reason mac side and protools m-powered windows side and it works fairly well for tracking bass lines. I haven't had any problems with the axiom, other than the pita that is assigning controller functions to an external controller in logic pro so I can use the transport keys on the axiom to run Logic. I just need a good dedicated bass pre, my mesa is a bit noisey. Been contemplating a PODxt or a Sadowsky Outboard. I'd also like to get a mini-me from apogee with the spdif output and some decent mic's for stereo x/y recording at some point....probably after I sell a kidney or get another student loan. Whichever comes first.