Yep, air leaks, even the open 1/4" jack can cause buzzing. Air leaks can be around speakers, jackplates, tears in a speaker cone, etc. Air can leak through a cracked joint if the cabinet has taken a really hard fall, and that can cause a bad buzz.
So can loose anythings, including internal wiring or sound absorbing insulation that has dropped so as to touch the cone.
or "tinsel leads" from frame to cone that are too loose and whip around hitting the cone. That can come from playing hard, but is actually an original defect.
A loose grille can buzz badly
A badly glued 'dust cap" in the center of the cone can cause buzzing if it comes loose. Again an original defect, but shows up when played for some time.
If you have REALLY played loud, you can "cook loose" the voice coil on one or more speakers. That causes a nasty buzz until the speaker finishes failing.
There are lots more, but those are examples.