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Pre-amp into tube head?

Either right in through the guitar regular or active input of the head, keeping the tube preamp in the path

Or Guitar pedal the AMP IN jack bypassing the tube preamp.

Experiment with both.

And you can use the effects loop: plug the guitar into the regular spot and insert the pedal: pre out to pedal and back to amp in. Thi option may not be best sounding but worth a try.