Short answer: Yes.
There are many threads here on solo strings tuned down. It works better with some strings than others and the success also depends on the sound and feel you are going for. Also, some basses sound better with higher tension, while some sound better with lower tension like you get with detuned solo strings.
Solo-gauge spirocores tuned down are quite popular among jazz players and some classical players. Some people like solo-gauge Dominants. In general strings that are higher tension and brighter at solo pitch will be more useable when detuned.
There are also some strings specifically designed to be used in either solo or orchestra tuning, such as Jargar Dolce and Velvet Compas 180 SUIT.
If you are planning on alternating between solo and orchestra tuning, you may need to adjust your string height a little to maintain a strong sound with the lower tension.