I suppose the real question being asked here is that with pedals like the VT bass and the darkglass, is it really worth it to carry 100lb heads just for the overdrive?
Power tube growl is off on another planet. Pedals are great, but in my opinion, they never will reach power tube growl. I used to love tube growl, but over time, the tube maintenance and the weight was not worth it for me.
It's all about the tone you want in a live setting.