From a feel and silent practice standpoint, it shouldn't make much of a difference at all. I wouldn't chalk up the guys with 4-bangers hating on or not being skilled enough to use a 6, there are just different things that are important to individual players. Extra strings can mean fewer string options (DEFINITELY higher string cost to move from a 4 to a 5 or more), difficulty for your amp + cab to reproduce a low B well, and differences in tension as compared to a 4 stringer. I play pretty hard and have strong hands so I like a little extra tension but don't necessarily want a .115 E string to get that. The absolute lowest we go is drop C#, so I can tune down with adequate strings and setup to get that low at a comfortable tension for me.
YMMV, the 6'er may be essential in your band or just plain feel better to you. Just wanted to give an opinion from the other side of the fence on why I and others may use 4's instead of 5's or 6's. Just some food for thought before you make the plunge
YMMV, the 6'er may be essential in your band or just plain feel better to you. Just wanted to give an opinion from the other side of the fence on why I and others may use 4's instead of 5's or 6's. Just some food for thought before you make the plunge

