Hey Matt,
I do gig with this rig. (two 210AVs) I actually stack them vertically so the top cab is at just about ear level. Sort of like the right or left side of an 810 cab. I usually run it with PAD out (0db), I run the Bass at about 3 o'clock, the mid at about 1-2 o'clock and the treble at 12 o'clock. I leave the limiter out too. Gain and Master are set accordingly. The Gain to whatever bass I'm using. Mostly a Lakland 55-01 or a Lakland JO4 passive. I also play an Alembic Elan 5 and an Orion 5 at times through it.
Keep in mind though. This is a great rig but it will not get you the Metallica gig. My playing situation is a 7 piece wedding band with good PA support. It's perfect for that. Anything louder and I need to add more power or more speaker surface. I've actually gigged with these two cabs and my CL and although it's overkill, it sounds awesome.
I have to say though that I really am loving the hell outta this little rig!! My chiropractor only sees me once a week now!
+1 on Jim C's suggestion too for checking phase. You can also have the store look into it as well.