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I had both. I kept the 2 Pro. As JimmyM said, it can do more stuff than the V4B. And it's 300W versus 100... Has a DI. Has a graphic EQ with a level boost (that you can bypass).
I'd do the same again (take the 2 Pro) - unless you just want to play at medium-to-medium-loud volume with a bunch of power tube grit in your sound, in which case, the V4B would be better for that. But, between the Master/Gain setup on the 2 Pro and the Drive knob, you can get a lot of grit without a lot of volume.
To me, the biggest problem, if you're looking for that certain power tube crunchy sound, is that there's more or less one volume on the V4B where you'll get it. If that's too loud for the room you're in, you'll have to turn down and lose that sound. If it's not loud enough for the room you're in, you have nowhere to go.