I was thinking about this topic today. Specifically, what kinds and what quantities of "thickening" (like modulations, pitch, ambience, and other washiness) can be added to a bass sound even to extremes, while still sounding like an organic instrument and not so much like a synth-- and also functioning like a bass in the mix, particularly with ballads or slow tempo long note stuff.
I have a Zoom MS-70CDR+ and there are lots of opportunities to stack & layer modulation, ambience, etc. And I could use the Portal to allow a dry mix/thru so low end could be protected.