I built (4) TL-606 cabs several years ago. Filled them with Altec 421-8H IIs, Typically just use (2) (Old School Acoustic 370). I have the port covers off, probably should try them with the covers on sometime, but ultimately, it is all about the sound YOU like. Not sure if the Cab is big enough for optimal tuning (with the 421s ) anyway. Side by Side, any Amp will fit on top, plus the sound isnt RIGHT in my ears. Light enough that I dont need to call someone to help me move them.
Another option you might want to try is the TL-505. Might be the size YOU'RE looking for. Heavier, Yes, but probably a better acoustic fit for 421s. I think this Cab was designed for 18s, but all you need to do is cut the baffle for a 15. I saw a Local Band use these, with 15s, as Subs for their PA. Lotsa Pant Leg Shakin goin on! Attached are the Plans. As always, optimal port tuning is everything.
Also a link for a Modification I found for a TL-806 (12 cab), but it might be a Good Mod to apply to the TL-606. And the Specs for an EV 2-15 Cab (couldnt find the plans). Good time of year for a project, as Im looking out at 8 inches of Snow!!
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GOOD LUCK!!!!