OK, I'll step in...
There are drawbacks: wider neck requires using really clean/proper technique (no "ape hanger" left hand technique), you have to pay very close attention to your right hand muting technique to keep any unplayed strings from inadvertently ringing out, and finally you have to deal with the pre-concieved notions of all those in your vicinity that want to judge you as a player before you've played your first note - "oh man, look at all those strings on his bass, I bet he overplays like a mofo!!
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Couldn't have said it better myself. I play 6's and 4's and I switched to 6's only months after getting my first bass. What I've noticed is that the 6's, like Gard said, force you to clean up your technique and that translates over into basses with fewer strings. That especially becomes apparent when slapping. Everything just gets tighter. 6's also just feel right too me; the width and thickness of the neck just make me feel at home.
One thing that I have found very difficult transferring over to 6's is Victor Wooten-esque "rhythmic slapping". Not the double thumping but the techniques he uses in songs like More Love, U Can't Hold No Groove, and Sex in a Pan. Learning to mute while doing suhc complex things is something that I'm struggling with but then again I've only been playing a few years. For someone with more experience, adapting may be smoother.
6's open up a whole different world of melodic, and chordal playign for those that choose to take advantage of it. Being able to do 2 octave scale in a single position keeps the variety coming and minimizes "vertical" fretboard movement, which gets a little confusing for me sometimes. As many doors as 6's open up I try not to depend on the the B and C strings and, instead, use them as extensions of or alternative to the notes on a normal 4 string. This way if you move between a 6 and a bass with less strings you don't feel lost or uncomfortable and can play what you played on the 6 just as easily on the 5 or 4.
I suggest getting a cheaper 6 for your first if you decide to try it out because though some people know right away whether or not they enjoy playing 6's, others may take their time in deciding so shelling out for a really something really nice could be a bad move if, ultimately, it turns out to not be your thing.
Yea I think that's about all I have to say on the subject. I hope you do move over to 6 because it really is a lot of fun... that and the more people that play 6 the less i'll hear "stop trying to be a guitarist
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