I have to agree that single coils and flats are a natural match. The chromes also respond very well to active electronics. I do think that chromes might also be more sensitive to neck construction and scale, and I imagine they would do really well on something like a dingwall. The low b is sounding very articulate on my cort so far at least to the 12th fret like the rounds did, will have to see how it holds up.
Since both split-coil-inside MK1 pup placement are more forward to bridge on Cort B5, i own one, sound thin with roundwound bass string. The mellow sounding Chrome just match it well,especially both E and B string .