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Do Plek machines slot bridge saddles?

I have a newish G&L JB 4 string that was factory Plek'd.

Since I got it I've noticed the E string sounds a bit different from the other strings, a bit more twangy, less solid fundamental.

Looking closely at the bridge today I see deep grooves cut in the saddles for the string to ride in. The E saddle groove seems somewhat off center, not level and kinda makes the E strings at an odd angle with where it leaves the string ball seat at the back of the bridge.

Not sure if this causing the different sounding E string or not.

Which led me to the question, Do Plek machines slot bridge saddles, or is this something else?