Boss ME 50B for me all the way! Have had several over the years, regretted selling them, so got another about a year ago. So overall my opinion is that is does more things right than it does wrong. The average person will most likely not use all of the features, but that is totally ok. In my mind this is like a cross sample of a fair amount of the Bass effects Boss makes. Being a turn the knob guy, it is perfect for me. I do not do patches, but it will do that. Very well built and a proven track record. I would use the A/C adapter for prolonged use, but it will run on batteries if needed. The Owners Manual is available PDF to view or download for free. If you do get a used one, be sure to do a factory reset, to get the previous owners “stuff” out of there. Method is in the Manual, pretty easy. You certainly can run other effects in conjunction with this, but put them AFTER the ME 50B.