HaHa - No I wouldn't. Some tube amps actually have shorting 1/4" jacks - so if you forget to plug in a speaker they don't destroy themselves.... "Pro-level gear" includes high end tube amps? I have yet to see a tube amplifier that has overcurrent/short circuit protection circuitry.
Most of the amps that do have protection circuits are solid state, and the protection circuits won't always detect a fault in time to avoid catastrophic failure.
Just my experience as a seasoned bench tech, and EE. YMMV!
My Mileage does vary.
It's like a Q-tip in the ear - when you hit resistance stop.
if you hear unplanned distortion - turn down.