I agree with the sentiment of "it depends on whose watts and through what". In general, a tube amp will sound louder than a solid-state amp at the same wattage through the same speakers. Also, speaker area is generally a bigger determinant of final volume than wattage. 50 watts per speaker will vibrate it quite nicely, and you get diminishing returns from increasing wattage per speaker (each additional watt provides less additional dB than the one before). That's not to say a 200-watt 2x10 is not going to sound louder than a 100-watt 2x10, but a 200-watt 4x10 will be louder than either 2x10.
The general rule of thumb, all other things being equal, is that you want twice the combined wattage of your guitarist's amps through as many speakers as it is feasible to buy, transport and fit on stage. If your guitarists both play through 100-watt half-stacks, you'll want a 400-watt half-stack. You might get away with less or need more depending on the enthusiasm of your drummer, additional amplified instruments like keyboards, how high your guitarists crank their amps, and whether you have reliable access to a PA that you can patch the amp into for more amplification.