Bull, like anything, it depends on the quality of the gear you're using. Some headphones are voiced to be relatively flat, some are not. And yes, full range systems would probably be closer to what you'd hear out of headphones, though bass cabs such as the fEarful have some voicing tweaks that would make them work more optimally for bass as opposed to things like PA cabs which are designed to put all the music through and not just bass.
So it's not a question that has cut and dried answers.
So it's not a question that has cut and dried answers.