So I have a weird issue where if I leave my computer alone for a while I need to reset my audio interface in order to hear any audio. I thought for sure that it was something to do with power settings and sure enough the "USB selective suspend setting" was set to enabled so I disabled it, but still had the problem. Then I opened the device manager and unchecked "Allow the computer to turn off this device to save power" on all of my USB Root Hubs. Problem persists. What I wind up having to do each time is turn off the interface, turn it back on and then "Scan for hardware changes" in the device manager and then it works fine. I have the latest driver installed. I'm running Win 7 Ultimate 64-bit in case anyone wanted to know. Any ideas?