Your first step to having a successful and awesome gig in San Francisco is to not call it San Fran. Not here, not anywhere. Break the habit now so you won't do it accidentally later.
As a San Franciscan, I can tell you, we are very particular. If you lower heaven and raise hell you will hear the sound of crickets from the audience if you call it San Fran.
The City, San Fran Effing Cisco or (marginally), Ess Eff are all fair game. San Fran or Frisco make you sound like you are trying too hard to be cool. We hate that.
Other than that, have the time of your life and let the audience know it. Practice your live moves in front of a mirror.
As a former San Franciscan (now in the East Bay -- WOOT! WOOT!), I can confirm Deep Cat's words of wisdom...
Call the city "San Fran," and you will feel NO LOVE.
You are doubly warned!!!
;-)